Perhaps a more proactive and valuable action would be what has happened in many university towns

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ead the following letter to the editor, in which there is an argument:
The University of Illinois and the City of Urbana recently decided to lower the speed limit on Lincoln Avenue between Pennsylvania and Nevada to protect the students who struggle to use responsible caution or to look up from their phones before they step out into the street in front of moving vehicles.
Again, these young adults are pandered to instead of being encouraged to be more responsible, under the guise of keeping them safe. Perhaps a more proactive and valuable action would be what has happened in many university towns: Make it illegal to be using any form of distraction while crossing the street by issuing a moving violation ticket.
I think this would be a better lesson to them than making the motorists responsible.
TANYA DECKERT
URBANA
(http://www.news-gazette.com/opinion/letters-the-editor/2018-08-12/letter-the-editor-young-adults-must-be-more-responsible.html (Links to an external site.)Links to an external site.)
Write a brief response to the letter (of about 1-2 paragraphs) in which you assess the merits of the author’s argument. Make sure you explain whether you think the author’s argument is good or not, and why.
 
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HITECH Legislation (Transforming Nursing and Healthcare Through Information Technology)For this Discussion you consider the impact of the meaningful use criteria of the HITECH legislation on the adoption of health information technology.

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HITECH Legislation (Transforming Nursing and Healthcare Through Information Technology)For this Discussion you consider the impact of the meaningful use criteria of the HITECH legislation on the adoption of health information technology.

In order for organizations to receive the incentives offered through the HITECH legislation they must be able to demonstrate that they are using the technology in meaningful ways. The following criteria for meaningful use must be evident to qualify for EHR incentives (U.S. Department of Health & Human Services 2012). The technology must:
For this Discussion you consider the impact of the meaningful use criteria of the HITECH legislation on the adoption of health information technology.
To prepare:
Post a description of how HITECH legislation has positively or negatively impacted your organization. Address how its related incentives influence the adoption of health information technology in health care and impact the quality of patient care. Provide a summary of the article you identified and explain how it demonstrates the ability of health information technology to meet the requirements of meaningful use.
1 &1/2 pages with 3 references from the below resources APA.
Required Readings
McGonigle D. & Mastrian K. G. (2015). Nursing informatics and the foundation of knowledge (3rd ed.). Burlington MA: Jones and Bartlett Learning.
Arlotto P. (2010). 7 strategies for improving HITECH readiness. hfm(Healthcare Financial Management) 64(11) 9096.
Retrieved from the Walden Library databases.
This article reviews seven strategies to help prepare for the implementation of the Health Information Technology for Economic and Clinical Health Act (HITECH). The central point of the article focuses on demonstrating meaningful use of electronic health records.
Begum R. Smith Ryan M. Winther C. H. Wang J. J. Bardach N. S. Parsons A. H. & Adams Dudley R. (2013). Small Practices Experience With EHR Quality Measurement and Incentives. American Journal Of Managed Care 19eSP128.
This article presents a study of clinicians attitudes toward the use of financial incentives for the implementation of electronic health records in small practices.
Brown B. (2010). The final rules for meaningful use of EHRs. Journal of Health Care Compliance 12(5) 4950.
Retrieved from the Walden Library databases.
In this article the author poses four questions pertaining to the EHR system in the United States. In particular the article examines Medicare and Medicaid incentive payments and the ways the meaningful use of certified EHRs will be verified.
Classen D. C. & Bates D. W. (2011). Finding the meaning in meaningful use. New England Journal of Medicine 365(9) 855858.
Retrieved from the Walden Library databases.
This article details the challenges of meeting the meaningful use standards in order to receive the benefits legislated under the HITECH Act. The authors specify the requisites for achieving benefits with EHRs the relationship between meaningful use and commercial EHRs and the tools needed to evaluate EHRs after implementation.
Kempfert A. E. & Reed B. D. (2011). Health care reform in the United States: HITECH Act and HIPAA privacy security and enforcement Issues. FDCC Quarterly 61(3) 240273.
Retrieved from the Walden Library databases.
The authors of this article examine HITECH in addition to the impact of the privacy rules under the Health Insurance Portability and Accountability Act (HIPAA). The article details the potential negative repercussions of failing to comply with HIPAA and HITECH.
Murphy J. (2010b). Nursing informatics. The journey to meaningful use of electronic health records. Nursing Economic$ 28(4) 283286.
Retrieved from the Walden Library databases.
This article reviews HITECH and the background leading up to its passage. The author also details the financial incentives intended to assist health care providers in purchasing and implementing HIT and EHR systems.
Optional Resources
U.S. Department of Health & Human Services. (2011). Health IT home. Retrieved from http://www.healthit.gov/
U.S. Department of Health & Human Services. (2012). Regulations and guidance. Retrieved from http://www.healthit.gov/policy-researchers-implementers/health-it-rules-regulations

 

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Introduction to Biochemistry

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Introduction to Biochemistry

4LMS0001

Interpretative assignment 2017-18

Your answers should be written in a Word document. This should only contain the text of the answers (and not the details of the experiments or the text of the questions). The maximum word count for the assignment is 1000 words. The work should be submitted electronically via StudyNet.

Objectives

· To introduce you to data interpretation and develop your interpretive skills.

· To show how metabolism can be studied.

· To show how studies of metabolism can be used to identify biochemical lesions.

· To develop your understanding of the glycolytic pathway.

Learning Outcomes

At the end of this exercise you should be able to:

· Understand what is meant by a U-14C label and how it can be used.

· Be very familiar with the glycolytic pathway.

· Understand some of the principles of the activation and action of toxicants.

· Have developed your ability to analyse data and think about metabolism logically.

Introduction

The glycoside beta drummin has been shown to be an effective reversible male anti-fertility agent in ram and boar. The primary contraceptive effect appears to be directly on spermatozoa within the cauda epididymis.

Adverse side effects have precluded human trials and it was decided to investigate the mechanism of action of beta drummin in order to develop less toxic anti-fertility analogues.

Radiolabelled substrates were used to elucidate where the compound was having an effect on metabolism. The substrates are designated U-14C which indicates that a proportion of the C atoms are the 14C isotope, U indicating that all the carbon atoms in the molecule are labelled rather than one specifically. The following experiments were carried out.

Experiment 1

Ram spermatozoa were washed in buffer (ram spermatozoa washed, RSW) and incubated for 3 hours with U-14C glucose (15mM) or U-14C fructose (10mM) in the presence of beta drummin (0.1mM). Oxygen uptake, as an indicator of aerobic respiration, was measured. Radioactivity recovered in the CO2 released as a result of oxidation of the substrate was also measured. Both were decreased to 50% in treated samples compared with control values. There was no accumulation of lactate.

Experiment 2

Incubation of RSW with U-14C pyruvate (5mM) or U-14C lactate (5mM) needed beta drummin at a concentration of 10-100mM to cause a 50% inhibition in oxygen uptake and 50% inhibition in CO2 released.

Experiment 3

Further incubations of RSW with inhibitor only, such that endogenous substrates (presumably lipid) are required for oxidation, resulted in negligible inhibition. Even when 100mM beta drummin was added the oxygen consumption was decreased by only 20%.

Experiment 4

RSW were incubated with fructose (15mM) in the presence and absence of beta drummin (3mM) and concentrations of glycolytic intermediates were measured. The results for samples treated with beta drummin, expressed as a percentage of control, are shown in Table 1.

Table 1: Concentrations of Intermediates of Glycolysis following incubation of RSW with beta drummin.

Concentration % of control value
glucose-6-phosphate 50 +/-2
fructose-6-phosphate 52 +/-3
fructose-1,6 bisphosphate 3,280 +/-100
dihydroxyacetone phosphate 280 +/- 20
glyceraldehyde-3-phosphate >300
3-phosphoglycerate Not detected*
2-phosphoglycerate Not detected*
phosphoenolpyruvate Not detected*
pyruvate 2 +/-0.1
lactate 0

* The assay method used could not detect these compounds in control or test incubates. In a separate experiment it was found that if two control incubates were pooled and the pooled volumes reduced by 50%, the assay method could just measure these compounds.

Experiment 5

Purified glycolytic enzymes were prepared from RSW and assayed for activity. Addition of beta drummin at final concentrations as high as 300mM to the reaction cuvettes had no effect on the activity of any of the glycolytic enzymes assayed including hexokinase, phosphofructokinase (PFK), aldolase, triose phosphate isomerise, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, pyruvate kinase and lactate dehydrogenase (LDH).

Questions

1. In just a few sentences explain how the 14C in the labelled glucose and fructose is incorporated into the CO2 released. (Only an overview, precise details of the pathways are not required.)

(10 marks)

2. What is the significance of the lack of accumulation of lactate in Experiment 1?

(10 marks)

3. What two explanations can you offer for the decrease in O2 uptake and CO2 output in the presence of beta drummin?

(10 marks)

4. Explain why the results of Experiment 2 point to some blockage of the glycolytic pathway by beta drummin.

(10 marks)

5. Explain why the results of Experiment 3 confirm the findings of Experiment 2.

(10 marks)

6. Suggest the probable site of beta drummin inhibition from the data in Table 1, explaining your reasoning.

(10 marks)

7. Give reasons why fructose-1,6 bisphosphate should be relatively so high.

(10 marks)

8. Postulate why beta drummin is effective as an inhibitor only when added to crude extracts but not when added to purified enzymes.

(10 marks)

9. What is the probable mechanism of inhibition shown when beta drummin acts in vivo?

(10 marks)

10. What is the physiological explanation for the anti-fertility effect of beta drummin?

(10 marks)

Guidelines

1) The total word count for the document is 1000 words.

2) The assignment should be typed, single-sided, double spaced in size 12 font. Please leave a standard margin on all edges (approximately 2.5 cm) and number the pages.

3) To facilitate anonymous marking please ensure your student number and word count are included in the header/footer of the assignment.

4) You should submit a document that has only the answers to each question (do not include the questions themselves).

5) You should submit a file that has only your student number as the filename.

6) Your name should not appear anywhere in the document.

7) Read through the information given and the questions at least twice before attempting your answers.

Failure to follow these guidelines will result in 5% being deducted from your overall mark.

The information is presented in a logical step-by-step way. Only consider the data for the specific experiment in each question, building on what you have already discovered, without including assumptions from later experiments.

4

 
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DISCUSS THE MAIN VIEWS OF NEOBEHAVIORISM.

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DISCUSS THE MAIN VIEWS OF NEOBEHAVIORISM.

Each response needs to have at least 175 words in APA format due 7/22/18 1 pm est. Needs to include a reference page (minimum of three)

1)Explain the main tenets of Behaviorism. Identify 3 ways Behaviorism influences the practice of psychology today.

2) Discuss the main views of Neobehaviorism. Identify 3 ways that Neobehaviorism influences the practice of psychology today.

3) Describe the concepts of Gestalt Psychology. Identify 3 ways Gestalt psychology influences the practice of psychology today.

4) Discuss the main views of Biological Psychology. Identify 3 ways that Biological Psychology influences the practice of psychology today.

5) Summarize Cognitive Psychology. Identify 3 ways that Cognitive Psychology influences the practice of psychology today.

Each response needs to have at least 175 words in APA format due 7/22/18 1 pm est. Needs to include a reference page (minimum of three)

Explain the main tenets of Behaviorism. Identify 3 ways Behaviorism influences the practice of psychology today.

Discuss the main views of Neobehaviorism. Identify 3 ways that Neobehaviorism influences the practice of psychology today.

Describe the concepts of Gestalt Psychology. Identify 3 ways Gestalt psychology influences the practice of psychology today.

Discuss the main views of Biological Psychology. Identify 3 ways that Biological Psychology influences the practice of psychology today.

Summarize Cognitive Psychology. Identify 3 ways that Cognitive Psychology influences the practice of psychology today.

 
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Nervous and Mental Disease

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Discussion

Imagine that you are a nurse in a large hospital. You have heard that there is new doctor in the psychiatry department but you have not met him. One day, you receive a call from Dr. Smith (the new doctor) telling you that he wants you to give Ms. Ruben, a patient, a dose of Astroten before he comes to examine her. He asks if you have it in stock and waits for your answer. You check the medicine shelf and find that you do have it and it clearly shows that the maximum dose should be 10 milligrams. He then orders you to give her 20 milligrams. Would you comply?

This was an actual field experiment under real world circumstances by Hofling, et al. (1966). Would it surprise you to know that 95% of the nurses who were called complied with the doctors order? This was true even though the dosage was clearly excessive and it was against hospital rules to take medication orders over the telephone.

Using what you have learned in this unit, can you explain the behavior of the nurses in this situation? Why did they obey the doctor even though they were breaking the rules and putting the patient at risk? Be sure to support your answer with information from the textbook or other appropriate psychology-specific sources. What implication does this have for hospital practices given the estimated 7700 deaths per year in the U.S. caused by medication errors in hospitals?

Reference:

Hofling, C., Brotzman, E., Dalrymple, S., Graves, N., & Pierce, C. (1966). An experimental study in nurse-physician relations.Journal of Nervous and Mental Disease, 143, 171–: 180.

 
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literature evaluation

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literature evaluation

Question descriptionIn nursing practice, accurate identification and application of research is essential to achieving successful outcomes. Being able to articulate the information and successfully summarize relevant peer-reviewed articles in a scholarly fashion helps to support the student’s ability and confidence to further develop and synthesize the progressively more complex assignments that constitute the components of the course change proposal capstone project.

For this assignment, the student will provide a synopsis of eight peer-reviewed articles from nursing journals using an evaluation table that determines the level and strength of evidence for each of the eight articles. The articles should be current within the last 5 years and closely relate to the PICOT statement developed earlier in this course. The articles may include quantitative research, descriptive analyses, longitudinal studies, or meta-analysis articles. A systematic review may be used to provide background information for the purpose or problem identified in the proposed capstone project. Use the “Literature Evaluation Table” resource to complete this assignment.

While APA style is not required for the body of this assignment, solid academic writing is expected, and in-text citations and references should be presented using APA documentation guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are not required to submit this assignment to Turnitin.

NRS-490-RS-LiteratureEvaluationTable.docx

 
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Five elements of the health care system that most need reform

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Discussion

Write a paper  that lists the top five elements of the health care system that most need reform, in your opinion. Justify your choices through a logical analysis of the elements’ impact on the current system. 1000-1200words

Refer to the assigned readings to incorporate specific examples and details into your paper.An Innovative Approach to Health Care Delivery for Patients with Chronic Conditions,” by Clarke, Bourne, Skoufalos, Beck, and Castillo, from Population Health Management(2017).  “Successful Strategic Planning for a Reformed Delivery System,” by Zuckerman, from Journal of Healthcare Management (2014). “Telemedicine and its Transformation of Emergency Care: A Case Study of One of the Largest US Integrated Healthcare Delivery Systems,” by Sharma, Fleischut, and Barchi, from International Journal of Emergency Medicine (2017). Reforming America’s Health Care Delivery System,” by Hackbarth, presented before the State Finance Committee Roundtable on Reforming America’s Health Care Delivery System (2009).

Prepare this assignment according to the APA guidelines

 
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development and maintenance of Substance Use Disorders.

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Answers must be paraphrased (restated in your own words with no quoting permitted), properly source credited, using APA formatting requirements – including within-answer citations and a list of references included at the end of each answer – and at least 600 words each, not counting source citations and references. Answers should be succinct, thorough, articulated in well-organized paragraphs (lists, sentence fragments and bulleted items are not permitted), and more substantive than just definitions of terms, procedures, or issues.
To complete these essay questions, construct your answers below each question on a separate page per question, attach a cover page to the front and a reference list to the end (references must also be placed at the end of each question for which they were used)
 
Questions:
1. Choose ONE of the following questions:
A. A friend says to you, “I’m really concerned about my child [an eight-year old girl] eventually developing an eating disorder. What should I do or not do?” Explain to your friend, using research-based findings and language he or she will understand, the avoidable – and possibly unavoidable – risks for the development of anorexia or bulimia.
B. The impact of culture and gender are important factors in the development and maintenance of Substance Use Disorders. Briefly describe some of the components of each of these factors and how they might be addressed in culture- and/or gender-specific treatment programs.
2. Accurately and appropriately diagnosing a sexual disorder or paraphilia can be among the most challenging tasks in clinical practice. Thinking about the 4 Ds as discussed in Week 1 of the course, choose ONE sexual disorder and ONE paraphilia covered in your text and discuss how applying those criteria could prove troublesome to a clinician. In addition, be sure to discuss any relevant gender and or cultural factors in terms of the diagnosis or the behavior itself.
3. Imagine you are a clinician at a community mental health clinic. Your client, who has been diagnosed with schizophrenia, has brought his mother in so the three of you can discuss his treatment options. Using general terms the client and his mother are sure to understand, describe the various types of (a) psychotherapy and (b) medications available for the treatment of schizophrenia, the types of symptoms they each treat, and their potential limitations and risks.
4. Two of the most common – and most troubling – of the personality disorders are antisocial personality disorder and borderline personality disorder. Compare and contrast these disorders. Be sure to cover the primary symptoms, predominant causal theories, and the possibility of gender bias in the diagnosis of these disorders. Last, suggest an effective course of treatment.
5. Choose ONE of the following questions:
a. Provide some compelling evidence that children aren’t simply “small adults” and that some separate diagnostic categories are necessary to accurately capture their psychological experience.
b. Psychological problems of the elderly can be divided into two groups: those that are unique to them and those that they share with other age groups. Discuss disorders of these two groups; be sure to indicate how disorders that occur in persons of all ages are nevertheless different in the elderly.
 
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Develop a one-paragraph case study related to domestic violence, child abuse, or elder abuse,

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please present an essay discussing the Purnell model its framework, assumptions which the model is based and how this model helps us to provide cultural competence health care.
please present your assignment in an APA format, word document, Arial 12 font , title “Week 2 discussion questions”.
You must present a minimum of two evidence-based references no older than 5 years to sustained your essay. the proper references are required and a minimum of 600 words
uestion description
Develop a one-paragraph case study related to domestic violence, child abuse, or elder abuse, including at least two pertinent discussion questions related to how the nurse would intervene appropriately.
Must be 250-300 words
Must be APA format

 
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Utilise the Clinical Reasoning Cycle (Levett-Jones 2013) (a clinical decision making framework) to plan and evaluate person-centred care Considering the persons situation collect process and present related health information

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Utilise the Clinical Reasoning Cycle (Levett-Jones 2013) (a clinical decision making framework) to plan and evaluate person-centred care Considering the persons situation collect process and present related health information

Case study/nursing care of the person
Order Description
You should discusses the provision and coordination of person-centred care linked to a real person you have cared for whilst on clinical placement (the essay can be written in a first person as this case study is my personal clinical placements experience).
Utilise the Clinical Reasoning Cycle (Levett-Jones 2013) (a clinical decision making framework) to plan and evaluate person-centred care Considering the persons situation collect process and present related health information Identify and prioritise at least three (3) nursing problems/issues based on the health assessment data that you have identified for the person at the centre of care in Recovery room (PACU) (for example: atrial fibrillation hypertension and postoperative pain) as a current serious problems (for example: patient had a hip replacement) Establish goals for priority of nursing care as related to the nursing problem/issues identified Discuss the nursing care of the person; link it to assessment data and history Evaluate your nursing care strategies to justify the nursing care provided Reflect on the persons outcomes
Marking criteria
Structure: The content in the case study matches the outline presented in the introductory paragraph. Paragraphs are organised and there is a logical progression of ideas so that content flows from one paragraph to the next. The case study ends with a rational conclusion.
Content: Comprehensively defines and discusses the provision of ethical legal evidence based and holistic person centred care including the establishment of realistic and relevant goals. Includes relevant discussion on the collection processing and presentation of client/patient information clearly identifies and prioritises nursing issues/ problems.
Critical thinking reasoning and evaluation of evidence: There is evidence of both depth and breadth of reading. A considered argument related to nursing care and issues/problems is presented and is supported by adequate and appropriate evidence.
Referencing: Credible and relevant (Australian sources 2010-2015) references are used. Accurate use of APA referencing style in all instances. A range of in-text citations has been used.

 

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