Asthma is a chronic lung disease caused by inflammation of the lower airways and episodes of airflow obstruction. Asthma episodes or attacks can vary from mild to life-threatening. In 2007, about 7% percent of the U.S. population was diagnosed with asthma and there have been a growing number of new cases since that time. There are several known risk factors identified as triggers of asthma symptoms and episodes, including inhalation of allergens or pollutants, infection, cold air, vigorous exercise, and emotional upsets. There is also growing evidence relating body-mass index to asthma in both children and adults. Design a study to investigate whether there is such an association.Choose a study design and justify the reasons you chose the design over others.Select a statistical measure you would use to describe the association (if there is one) between body mass index and asthma.In addition, address:1. Subject selection2. Issues relating to the measurement of both the exposure and the outcome3. Potential biases that the study might be prone to, and how they might be handled4. Possible confounding factors and effect modifiers and how to overcome their effect.Present the information in a 750-1000-word report, using section headings where each requirement is described and justified under each of the following headings: Study Design, Statistical Measures, Subject Selection, and Measurement Issues.Refer below to the “Key Elements of a Research Proposal.”You are required to use a minimum of three scholarly resources.Prepare this assignment according to the APA guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.Key Elements of a Research ProposalIf you need a review of study design components, view the resources below.Review the Key Elements page of the Research Methods Knowledge Base website at Social Research Methods – Knowledge Base – Key ElementsSocial Research Methods – Knowledge Base – Key ElementsKey Elements of a Research ProposalBackground / purpose / rationale of the studyLiterature reviewHypothesis/key questionsResearch objectivesResearch methodsStudy designStatistical biasProcedures/timelineSpecific steps to be taken to complete the studyInstruments/data collection methodsOutcomesProposed data analysis planStatistical analyses plannedPower analysis if appropriateData safety monitoring if appropriateStudy participantsDescription of participatesRecruitment of participatesConfidentiality/human subject’s protection/legal-ethical issues (if appropriate)Sampling / rationaleInclusion/exclusion criteriaNumber of subjectsStatistical Analysis (only if applicable)Anticipated Results and Potential PitfallsImplications for PracticeAdapted from “Key Elements of a Social Science Research Proposal: Statement of Research Plan” by the Office of Research at Northwestern University at www.research.northwestern.edu
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